Note: The job is a remote job and is open to candidates in USA. Tarsus Pharmaceuticals is a pharmaceutical company focused on developing eyecare therapies. The Sr Director, Clinical Sciences will lead the Clinical Science function and oversee the scientific integrity, quality, and strategic impact of eyecare clinical studies from early development through registration and lifecycle management. The role will guide clinical development plans, trial designs, cross-functional teams, regulatory documentation, data interpretation, and stakeholder engagement.
Responsibilities
- Provide scientific leadership to cross‑functional study and program teams, ensuring timely study start‑up, enrollment, database lock, analysis, and readouts
- Lead the design of clinical development plans and individual study protocols (objectives, endpoints, inclusion/exclusion, assessments, statistical assumptions)
- Maintains direct ownership of clinical deliverables, actively contributing to protocol development, document authoring, data review, study-level problem solving and execution decisions to ensure scientific rigor and operational excellence
- Shape clinical plans including timelines, budgets and oversight of clinical teams
- Build and maintain strong relationships with investigators, KOLs, and external partners; contribute to publication strategy and scientific communications
- Drive innovation in clinical endpoints, biomarkers, and digital tools, and champion continuous improvement in clinical science processes, templates, and data review frameworks
- Author and critically review key clinical and regulatory documents, including protocols, SAPs, CSRs, IBs and clinical value dossiers, ensuring scientific rigor, regulatory alignment and quality execution
- Conduct research to develop foundational education material to inform the early development program strategies
- Interpret clinical data and support data-driven decisions
- Serve as program lead on early development Core teams, investigator meetings and scientific advisory boards
- Engage with internal and external stakeholders, including KOLs and regulators
- Exhibits and fosters key leadership competencies, including an innovative mindset, strong business acumen, an outcome-driven orientation, and a commitment to growing and expanding the capabilities and capacity of the team
- Collaborate with Clinical Operations, Regulatory Affairs, Translational Sciences, Biostatistics, Medical Affairs and others to ensure robust trial design, scientific and operational alignment and execution
Skills
- Advanced degree in sciences (e.g. PharmD, MD, PhD) with deep experience in early clinical development
- Minimum of 10 years of biotech/pharmaceutical clinical development experience, with a minimum of 8 years leadership in clinical trial management experience required
- Established leadership track record with evidence of excellent performance-based people management experience, problem solving, collaboration, cross functional leadership and effective communication skills
- Expertise with SOPs, GCPs and regulatory and compliance guidelines for clinical trials
- Must be willing to be “hands on” and delve into details
- Some travel may be required – up to 30%
- Experience in ophthalmology is preferred; dermatology or infectious diseases a plus
- Remote work is an option
Benefits
- Bonus
- Stock equity
- Health, dental and vision insurance benefits
- Generous paid time off, including vacation, holidays, and personal days
- Onsite gym
- Pool
- Snacks
- Drinks
- Occasional catered meals
- Hybrid work environment
- Remote work is an option
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