Note: The job is a remote job and is open to candidates in USA. Alnylam Pharmaceuticals is a leader in RNAi therapeutics, seeking a highly skilled Senior Associate Scientist, Pharmacometrics to optimize and scale data workflows supporting drug development. The role involves streamlining analytical processes, developing code and tools, and collaborating with various teams to enhance pharmacometric analyses.
Responsibilities
- Streamline data cleaning, transformation, and QC processes to improve reproducibility, traceability, and robustness of analytical workflows
- Design, develop, and maintain reusable, well-documented code, libraries, and utilities in R and/or Python to support scientific analyses
- Create interactive tools or dashboards to support internal users (e.g., Shiny, Dash)
- Apply software engineering best practices (version control, testing, modular design)
- Communicate user needs with the vendor
- Collaborate with IT and the vendor to support change controls
- Work closely with pharmacometricians to support PK/PD and exposure–response analyses
- Learn foundational PK/PD and modeling concepts on the job
- Translate scientific requirements into robust computational solutions
- Enable faster iteration and insight generation for modeling and simulation activities
- Partner with Clinical Pharmacology, Statistics, and related quantitative groups
- Support data standards, organization, and metadata practices
- Communicate technical solutions clearly to both technical and non-technical colleagues
Skills
- MS in Data Science, Computer Science, Statistics, Applied Mathematics, Engineering, or related quantitative field
- Strong programming background in R and/or Python
- Demonstrated experience optimizing, automating, or scaling data analysis workflows
- Experience working with complex scientific or real-world datasets
- Solid understanding of data structures, algorithms, and analytical best practices
- Exposure to regulated environments and audit-ready workflows
- Strong problem-solving skills and curiosity
- Prior exposure to pharmacometrics, biomedical data, or clinical data would be a plus
Benefits
- Annual short-term incentive award (e.g., bonus or sales incentive)
- Annual long-term incentive award (e.g., equity)
- Medical, dental, and vision coverage
- Life and disability insurance
- A lifestyle reimbursement program
- Flexible spending and health savings accounts
- A 401(k)with a generous company match
- Paid time off
- Wellness days
- Holidays
- Two company-wide recharge breaks
- Generous family resources and leave
Company Overview