Note: The job is a remote job and is open to candidates in USA. Centessa Pharmaceuticals is a clinical-stage company developing orexin receptor 2 agonists for narcolepsy and other sleep-wake disorders. The Manager, Clinical Supply Chain will support end-to-end clinical supply planning and execution, ensuring uninterrupted investigational product, comparator, and ancillary material supply while coordinating with internal teams and external vendors. The role focuses on forecasts, inventory systems, IRT tools, compliance, and clinical trial timelines.
Responsibilities
- Contribute to the development and execution of clinical supply strategies for early- to mid-phase clinical trials (Phase 1–3 as applicable)
- Manage clinical supply plans, demand forecasts, and inventory strategies — including tracking through Interactive Response Technology (IRT) systems — in alignment with protocol requirements and enrollment projections
- Support packaging, labeling, distribution, and resupply activities for investigational products and comparators
- Ensure on-time delivery of clinical supplies to depots and clinical sites globally
- Partner with Quality, Clinical, CMC, and external CDMOs to develop, review, and approve clinical labels, and support CDMO packaging/labeling schedules to ensure supply availability
- Interact regularly with third-party providers to manage the logistics and licenses required to ship materials from manufacturing to bulk storage facilities, courier depots, and investigator sites
- Collaborate with CMC and QA to facilitate the document transfer required for IP/QP release by CDMOs
- Monitor shelf-life and expiry dating, and coordinate retest/extension activities with the analytical team to ensure continuous supply
- Manage the investigation, reporting, and communication of outcomes from temperature excursions and product complaints
- Support product recovery activities pending investigation of IP from investigator sites, as needed
- Communicate effectively across functional areas, applying a solid working knowledge of clinical supply chain processes
- Author Pharmacy Manuals for clinical studies, as needed
- Represent Supply Chain in Clinical and CMC Sub-Team meetings
Skills
- Bachelor's degree in engineering or science required
- 3–5 years of biotech/pharma industry experience in clinical supply chain, including international experience, required
- Working knowledge of clinical supply chain processes and GMP/GDP requirements
- Experience coordinating cross-functional project teams and external vendors
- Strong organizational, analytical, decision-making, and interpersonal skills, with excellent attention to detail
- Ability to work independently in a fast-paced, dynamic environment
- Demonstrated ability to coordinate CDMO activities supporting clinical development of pharmaceutical products
- Ability to thrive in a small-company culture and contribute to creating and implementing processes
- The Manager, Clinical Supply Chain role is a remote role based in the US, with occasional travel (up to 20%)
Benefits
- Discretionary annual bonus
- 401(k) plan
- Company-sponsored medical, dental, vision, and life insurance
- Generous paid time off
- Health and wellness program
- Remote role based in the US
Company Overview
Company H1B Sponsorship