Note: The job is a remote job and is open to candidates in USA. Immatics is a biotechnology company advancing cancer immunotherapy through precision-targeted therapies. The Clinical Trial Manager will support U.S. Clinical Operations by overseeing site management, monitoring activities, and clinical trial execution while ensuring compliance with GCP, regulatory requirements, and company SOPs.
Responsibilities
- Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities in alignment with project goals
- Lead site feasibility, selection, initiation, and greenlight activities for clinical trial sites
- Develop and maintain study-specific operational plans, training materials, and monitoring documentation
- Oversee site management activities, including site engagement, regulatory submissions, and monitoring oversight
- Review trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectives
- Provide guidance and oversight to CRAs, including trip report review and training support
- Manage protocol and GCP deviations and contribute to continuous improvement of clinical operations processes and procedures
Skills
- Bachelor's degree in life sciences, nursing, or a related field
- 2+ years of experience in on-site clinical monitoring and 2+ years of Clinical Trial Manager experience within the pharmaceutical or biotechnology industry
- Strong knowledge of ICH-GCP, FDA, EMA, and applicable clinical trial regulations
- Demonstrated experience managing clinical trial sites, monitoring activities, and regulatory documentation
- Proficiency with clinical trial systems and tools (e.g., CTMS, eTMF, Microsoft Office)
- Travel required:**up to 50% travel required, domestically and internationally
- Applicants must be authorized to work in the United States without the need for current or future sponsorship
- Experience in oncology clinical trials or related therapeutic areas
- Advanced ability to manage complex clinical operations processes and drive operational improvements
- Experience leading training initiatives for CRAs and clinical trial sites
- Demonstrated ability to drive quality, efficiency, and milestone achievement in fast-paced clinical environments
- Experience contributing to process harmonization, innovation, and continuous improvement initiatives
- Strong presentation, organizational, and cross-functional stakeholder management skills
Benefits
- Competitive rates for Health, Dental, and Vision Insurance
- 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
- 12 company paid holidays
- 7 days of sick time
- 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
- 100% employer-paid short- and long-Term disability coverage
- 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
- Partially paid parental leave for eligible employees.
- Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.
- Fully Remote
Company Overview