About Aura Biosciences
Aura Biosciences is a clinical-stage biotechnology company developing bel-sar, a potentially transformative, first-in-class therapy for patients living with ocular cancers. Bel-sar represents an entirely novel approach to treating ocular cancers via its dual mechanisms of action of acute tumor necrosis and secondary anti-tumor immune activation. The Phase 3 registration study of Bel-sar in early choroidal melanoma, the largest patient segment of uveal melanoma, is fully enrolled, and earlier stage studies in metastases to the choroid and cancers of the ocular surface are ongoing. Aura's mission is to improve outcomes for patients living with ocular cancers by delivering a therapy that not only arrests tumor growth but also preserves vision and quality of life.
For more information, visit aurabiosciences.com. Follow us on X, @AuraBiosciences, and visit us on LinkedIn.
Position Summary
Aura Biosciences is seeking a highly motivated Clinical Scientist, Contractor to join our Clinical Development organization.
The Clinical Scientist will be a key scientific member of cross-functional study teams, contributing to the design, execution, analysis, interpretation, and communication of Aura's clinical programs. Working closely with the Vice President Clinical Development and colleagues across Medical, Clinical Operations, Biostatistics, Safety, Data Management, Regulatory, and other functions, this individual will help translate clinical strategy into high-quality studies and actionable scientific evidence.
The successful candidate will combine strong scientific and clinical judgment with a hands-on approach to clinical data, study execution, and cross-functional problem solving.
Key Responsibilities
Clinical Data Review and Study Execution
- Conduct ongoing review and interpretation of clinical trial data, including safety, efficacy, study conduct, and data quality.
- Identify emerging clinical trends, inconsistencies, and data issues and work cross-functionally and proactively to drive timely resolution.
- Partner with Biostatistics and Data Management on data review plans, patient profiles, listings, tables, figures, data cleaning, and database lock activities.
- Serve as a clinical-science resource for study teams and partner with Clinical Operations to support high-quality study execution.
Clinical Development and Regulatory
- Contribute clinical and scientific input to clinical development plans, study design, and analysis approaches.
- Author and/or contribute to protocols and amendments, clinical study reports, investigator brochures, regulatory briefing documents, health authority responses, and other key clinical documents.
- Evaluate emerging clinical data, scientific literature, and competitive programs to inform study and development strategy.
- Ensure clinical data and scientific rationale are presented clearly, accurately, and consistently across clinical and regulatory deliverables.
Scientific Communication
- Develop clear presentations of clinical data for study teams, internal governance, and external scientific audiences.
- Contribute to abstracts, posters, presentations, manuscripts, and other scientific communications.
- Maintain current knowledge of ocular oncology, ophthalmology, oncology drug development, and the evolving therapeutic landscape relevant to Aura's programs.
Cross-Functional Collaboration
- Collaborate effectively across Clinical Development, Clinical Operations, Biostatistics, Data Management, Safety, Regulatory Affairs, and other functions.
- Communicate clinical insights, risks, and recommendations clearly and bring a patient-focused, evidence-based perspective to decision-making.
- Help develop fit-for-purpose clinical-science processes and ways of working appropriate for a growing biotechnology company.
- Demonstrate scientific rigor, accountability, flexibility, and a willingness to work across traditional functional boundaries.
Qualifications
- Advanced degree in a relevant scientific or health-related discipline (PhD, PharmD, OD, or equivalent) strongly preferred; candidates with an MS, MPH, or other relevant advanced degree and substantial clinical development experience may also be considered.
- 3+ years of relevant experience in clinical research or drug development within biotechnology, pharmaceuticals, or medical devices.
- Experience supporting the conduct, analysis, and reporting of interventional clinical trials.
- Demonstrated ability to review and interpret clinical and scientific data and translate findings into clear conclusions and recommendations.
- Strong understanding of clinical trial methodology, GCP, and relevant regulatory requirements.
- Strong scientific writing, presentation, communication, and cross-functional collaboration skills.
- Ability to take ownership, manage multiple priorities, and deliver high-quality work in a fast-paced, evolving environment.
Preferred Experience
- Experience in ophthalmology, oncology, or rare disease drug development.
- Experience with Phase 2 and/or Phase 3 clinical development.
- Hands-on experience with efficacy and safety data review, including patient profiles, listings, tables, and figures.
- Experience contributing to regulatory submissions or interactions with health authorities is a plus.
Travel
Ability to travel domestically and internationally as required for study activities and other business needs. Expected travel approximately 10–20%.
Contract Expecations:
Remote role in UK (not limited to London posting location)
Must be physically located in UK
Full time weekly hours (40 hours per week)
Expectations for year-long contractor (possibility for both/either extention/conversion depending on business need)
Must be authorized to work legally in UK
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